Our mission is to bring HOPE to those impacted by Duchenne Muscular Dystrophy.

We fund DMD research and strive to enhance the quality of life for those impacted by Duchenne.

Austin's Family

Tim, Amber, Austin & Ayla Nisley

Austin's Hope was founded to honor our son, Austin, and all the brave boys and courageous families fighting Duchenne Muscular Dystrophy. Through our charity we take action, raise awareness, and provide support to fellow DMD families, demonstrating our love and commitment to this cause. Our faith remains our foundation as we strive to "move mountains" in our fight against DMD.

We are grateful for your support and for joining us on this journey.

What is Duchenne?

Duchenne Muscular Dystrophy (DMD) is a severe, genetic, progressive, muscle-wasting disease. One in every 3,500 to 5,000 boys born is diagnosed with Duchenne. Males are primarily affected, but in rare cases, it can also affect females.

  • Without dystrophin, muscle wastes away, leading to severe physical limitations

  • DMD symptoms are usually identified between the ages of two and three. Children could have difficulty rising from the floor, climbing stairs, maintaining balance, and walking. They fall frequently, lack endurance when walking or playing, and may not be able to run or jump.

  • Come elementary age, children with Duchenne will likely need a mobility device to participate in daily activities. By 8 to 12 years of age, they often lose the ability to walk.

  • As Duchenne progresses, the upper body weakens, leading to dependence on others for eating, bathing, toileting, and most day-to-day necessities.

  • It's caused by a mutation in the gene that creates dystrophin, ceasing production of this vital protein

The Science.

Duchenne Muscular Dystrophy (DMD) is a crippling disease that progressively attacks the body’s muscles, and ultimately takes boys’ lives by attacking the muscles in their heart and lungs.

Duchenne Muscular Dystrophy (DMD) is caused by mutations in the gene that encodes the protein dystrophin. Dystrophin is essential for maintaining the integrity and stability of muscle fibers. Without it, the muscle fibers become damaged and eventually die, leading to progressive muscle weakness and wasting.

The dystrophin gene is located on the X chromosome, which means that DMD is an X-linked recessive disorder. This means that the gene mutation causing DMD is carried on the X chromosome, and because boys only have one X chromosome, they are more likely to develop the condition than girls. Girls can also be carriers of the gene mutation and may have milder symptoms or no symptoms at all.

There are different types of mutations that can occur in the dystrophin gene, ranging from small changes in the DNA sequence to large deletions or duplications of entire regions of the gene. The type and location of the mutation can affect the severity of the condition, with larger deletions typically associated with more severe symptoms.

The progressive muscle weakness and wasting in DMD is caused by the loss of muscle fibers and the replacement of muscle tissue with fat and connective tissue. This leads to a gradual decline in muscle function and mobility, as well as a range of associated complications such as respiratory and cardiac problems.

Although there is currently no cure for DMD, research is ongoing to develop new treatments and therapies that can help slow or halt the progression of the condition and improve the quality of life for affected individuals.

What is Duchenne?

Duchenne Muscular Dystrophy (DMD) is a genetic disease that results in severe muscle wasting and debilitation. The condition gradually impairs basic body functions, such as walking and running. Eventually, individuals may lose the ability to perform simple tasks like feeding and bathing. Those diagnosed with DMD will eventually succumb to heart and lung failure, leading to a shortened life expectancy.

  • Individuals living with DMD will lose their life to heart and lung failure, leading to a shortened life.

  • Until recently, those living with Duchenne did not survive much past teen years.

While there is currently NO CURE for Duchenne Muscular Dystrophy, there is still HOPE.

Thanks to ongoing research and advancements in medical care, we are closer than ever before to finding a cure for this devastating disease. With your support, we can make a difference and bring an end to Duchenne.

Meet Austin

Austin was diagnosed with Duchenne Muscular Dystrophy (DMD) in the fall of 2016 at the age of three. Though living with DMD presents obstacles, Austin loves spending time with family & friends, playing video games and being outdoors, and doing anything that your average 10-year-old would.

Austin was fortunate to have the opportunity to participate in a gene therapy clinical trial at Nationwide Children's Hospital. The hope is that this treatment is successful by slowing the disease progression and is ultimately available to all children battling this fatal disease.

Will you join us on our journey?

Your donations play a vital role in enabling us to fulfill our mission of bringing HOPE to individuals and families affected by Duchenne Muscular Dystrophy.

By partnering with us, you can help provide access to electric trikes, video gaming systems, mobility devices, wheelchair ramps, and home modifications that can significantly improve an individual's independence and overall well-being. Additionally, your contribution will help fund critical research initiatives that are focused on finding a cure for DMD. Every dollar donated can make a significant impact and bring us one step closer to ending this devastating disease.

Research Dollars

Money raised will fund crucial research treatments just like the one Austin was able to receive.

There is currently NO CURE!

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Fun, Freedom & Functionality Dollars

We believe that everyone deserves the opportunity to live life to the fullest, regardless of their physical limitations. That's why we provide a range of resources to support individuals with Duchenne, including electric trikes, gaming systems, wheelchair ramps, mobility scooters, stair lifts, and unique experiences.

Save the Date!

Austin's Night of Hope 2024

Saturday November 23, 2024

2023 Gala Photos!

About Austin's Hope

Upcoming Events

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Austin's Night of Hope

Ticket Sales Open Mid-Summer 2023

Saturday November 18, 2023
7pm - 10pm, Tickets $150/pp

Polaris Co-hatch, 1554 Polaris Pkwy #325, Columbus, OH 43240

Cocktails & Hors D'oeuvres

Live Music

Silent Auction, Wine Pull, 50/50 Raffle

BE A NIGHT OF HOPE EVENT SPONSOR!

All Donations are Tax Deductible

Individual
Sponsor

$500/min

  • Name on Event Signage

  • Name in event program

  • Austin's Hope Shirt



Corporate Sponsor

Level 1

$1000

  • 2 Event Tickets

  • Logo on Group Sign at Event

  • Social Media Recognition

  • Logo in Event Program

Corporate Sponsor

Level 2

$2500

  • 2 Event Tickets

  • Signage at Event

  • Social Media Shout Outs

  • Logo in Event Program

  • Austin's Hope Shirt

Ultimate Austin Sponsor

$5000

  • 2 Event Tickets

  • Logo in Event Program

  • Verbal Recognition at Event

  • Individual Signage at Event

  • Logo on step & Repeat

  • Logo on Event tV's & Screens

  • Recognition on website

  • Individual Social Media Posts

  • Bottle of Austin's hope wine from paso robles, cA

  • Austin's Hope Swag Bag

Partner with us by becoming an Austin's Hope sponsor!

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Level 1

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Ultimate Austin

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Level 2

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Just A Little Help Can Make Their Hearts Happier.

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We don't have TIME but we do have HOPE...

Help us MOVE MOUNTAINS to

END DUCHENNE with a tax-deductible donation. Click button or scan QR below to donate.

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